Production of polyphenol extracts of plant origin
with antiplatelet and cardioprotective properties
FLAWOPIRYNA
Aim of the project
The objective of the project is to work out three polyphenol extracts of plant origin (two new generation diet supplements and one active medical ingredient), which will show antiplatelet and cardioprotective properties. The project aims at production of innovative and competitive products, which can potentially be useful in the prevention and therapy of cardiovascular diseases.
Project objectives
• to determine antiplatelet properties of extracts
• to determine cardioprotective properties of extracts
• to determine cell cytotoxicity of extracts
• to determine other biological properties of extracts
• to determine the biological safety of Extracts.
Methods
Extracts are isolated from plants of Polish origin.
Antiplatelet and cardioprotective properties are assessed using flow cytometry, platelet aggregometry, and molecular biology methods assayed in human blood, cell cultures and animal models.
General information
Project supported by Structural Funds of EU, Operational Programme Innovative Economy –
Research and Developement of ModernTechnologies
- Total support over $ 2,5 mln
- Over 30 scientists involved
- Project duration: 3 years (2009 –2012)
Scientific Consortium
Project Leader: Medical University of Lodz
Department of Haemostatic Disorders
Participants:
Technical University of Lodz
Department of Biotechnology and Nutrition
University of Lodz
Department of General Biophysics
Key persons
Managing Board:
Prof. Cezary Watała cezary.watala@umed.lodz.pl
Dr Marcin Różalski marcin.rozalski@umed.lodz.pl
Ass. Prof. Jacek Golański jacek.golanski@umed.lodz.pl
Project Manager:
Mikołaj Gurdała mikolaj.gurdala@umed.lodz.pl
Authorities of the Medical University of Lodz:
Rector: Prof. Paweł Górski
Rector’s representative for University Development and Promotion
Przemysław Andrzejak przemyslaw.andrzejak@umed.lodz.pl
Business partners
Polish biomedical/pharmaceutical companies cooperating closely with the participants of the Project
Summary
The results of the project will be patented and implemented to production by the pharmaceutical industry. In general, the project combines science and business, giving a chance for new employment and development in the region.
Project Office
ul. Stefanowskiego 12/16
90-924 Łódź
tel. +48 42 6313868
fax. +48 42 6313868
e-mali: biuro@flawopiryna.pl
www.flawopiryna.pl
